{"id":4186,"date":"2024-03-12T11:39:00","date_gmt":"2024-03-12T11:39:00","guid":{"rendered":"https:\/\/nish.wales\/?p=4186"},"modified":"2026-03-12T11:48:15","modified_gmt":"2026-03-12T11:48:15","slug":"case-study-a-review-of-capsule-formulations-and-extended-release-pepsin-mechanisms","status":"publish","type":"post","link":"https:\/\/nish.wales\/cy\/2024\/03\/12\/case-study-a-review-of-capsule-formulations-and-extended-release-pepsin-mechanisms\/","title":{"rendered":"Astudiaeth Achos: Adolygiad o Fformwleiddiadau Capsiwl a Mecanweithiau Pepsin Rhyddhau Estynedig"},"content":{"rendered":"<p class=\"wp-block-paragraph translation-block\"><strong>Mae <a href=\"http:\/\/www.argip.co.uk\/\" target=\"_self\">ARGiP Technologies Ltd<\/a> o Ben-y-bont ar Ogwr yn cynhyrchu technolegau a deunyddiau crai ar gyfer diagnostig, cosmetig, a defnydd ategol.\u00a0<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Cysylltodd ARGiP \u00e2 <a href=\"https:\/\/www.swansea.ac.uk\/medicine\/enterprise-and-innovation\/business-support-projects\/accelerate-healthcare-technology-centre\/\" target=\"_self\">Chanolfan Dechnoleg Iechyd Gofal<\/a> (HTC) Prifysgol Abertawe i ofyn am gymorth drwy\u2019r Rhaglen Cyflymu i atgyfnerthu\u2019r ddealltwriaeth o fioleg pepsin er mwyn helpu i ddatblygu atodiad pepsin wedi\u2019i fireinio ar gyfer y cwmni.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mae Pepsin yn ensym stumog sy'n torri bwyd i lawr. Fe'i cynhyrchir ym mhrif gelloedd gastrig leinin y stumog ac mae'n un o'r prif ensymau treulio yn systemau treulio bodau dynol a llawer o anifeiliaid eraill, lle mae'n helpu i dreulio'r proteinau mewn bwyd.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mae capsiwlau cragen feddal a chragen galed yn chwarae rhan arwyddocaol wrth ddosbarthu cyffuriau ac atchwanegiadau trwy'r geg. Fodd bynnag, mae'r ymchwil ynghylch cyflenwi atchwanegiadau llafar yn ddiffygiol ac mae angen rhoi sylw iddo. Heriwyd HTC i ddarparu dealltwriaeth glir o'r broses amg\u00e1u a darparu gwybodaeth fanwl am y gwahanol fecanweithiau rhyddhau estynedig a ddefnyddir systemau dosau llafar, gan gysylltu'r canfyddiadau hyn ag amg\u00e1u pepsin.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mae'r ymchwil sy'n ymwneud \u00e2 chynhyrchu a llenwi ffurflenni dos capsiwl yn mynd y tu hwnt i gwmpas yr adolygiad hwn. Fodd bynnag, mae HTC wedi nodi'r cysyniadau allweddol o fewn y broses gynhyrchu a llenwi sy'n ymwneud \u00e2 pepsin. Mae\u2019r cydweithrediad hwn wedi ysgogi ymchwil a dealltwriaeth y cwmni o fioleg pepsin, technoleg capsiwl, a fformwleiddiadau.&nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bydd yr ymchwil hwn yn chwarae rhan allweddol yn natblygiad atodiad pepsin mireinio ARGiP a allai arwain at dwf cwmn\u00efau a chreu mwy o swyddi yng Nghymru.<\/p>","protected":false},"excerpt":{"rendered":"<p>Bridgend-based ARGiP Technologies Ltd manufacture technologies and raw materials for diagnostic, cosmetic, and food complements use.\u00a0 ARGiP contacted Swansea University\u2019s Healthcare Technology Centre (HTC) seeking support via the Accelerate Programme to consolidate the understanding of pepsin biology to aid in the development of a refined pepsin supplement for the company. Pepsin is a stomach enzyme [&hellip;]<\/p>\n","protected":false},"author":190346150,"featured_media":4187,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_wpcom_ai_launchpad_first_post":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1367],"tags":[1375,1368],"class_list":["post-4186","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-case-study","tag-health","tag-research"],"jetpack_publicize_connections":[],"jetpack_likes_enabled":false,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pfwlnl-15w","jetpack-related-posts":[{"id":2827,"url":"https:\/\/nish.wales\/cy\/2025\/04\/23\/case-study-new-funding-to-tackle-ovarian-cancer-resistance\/","url_meta":{"origin":4186,"position":0},"title":"Astudiaeth Achos: Cyllid Newydd i Ddatrys Ymwrthedd i Ganser yr Ofar\u00efau","author":"meganchick1","date":"23rd Ebrill 2025","format":false,"excerpt":"Despite decades of research and medical advances, treatment options for high-grade serous ovarian cancer - the most aggressive and common form of the illness - remain largely unchanged since the 1950s. However, new research led by Associate Professor James Cronin at Swansea University is aiming to change this with funding\u2026","rel":"","context":"In &quot;Case Study&quot;","block_context":{"text":"Case Study","link":"https:\/\/nish.wales\/cy\/category\/case-study\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2025\/04\/Wordpress-1-2.png?fit=1200%2C628&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2025\/04\/Wordpress-1-2.png?fit=1200%2C628&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2025\/04\/Wordpress-1-2.png?fit=1200%2C628&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2025\/04\/Wordpress-1-2.png?fit=1200%2C628&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2025\/04\/Wordpress-1-2.png?fit=1200%2C628&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":4215,"url":"https:\/\/nish.wales\/cy\/2024\/03\/13\/case-study-combining-biology-and-software-to-help-people-live-better\/","url_meta":{"origin":4186,"position":1},"title":"Astudiaeth Achos: Cyfuno bioleg a meddalwedd i helpu pobl i fyw'n well","author":"meganchick1","date":"13th Mawrth 2024","format":false,"excerpt":"Glucose Republic\u00a0is combining biology and software to help people eat and live better through the means of\u00a0tracking and monitoring how blood glucose responds to different nutrition in real-time\u00a0circumstances. Each of us has a unique food fingerprint which we can access via our own glucose response to food and exercise\u00a0and this\u2026","rel":"","context":"In &quot;Case Study&quot;","block_context":{"text":"Case Study","link":"https:\/\/nish.wales\/cy\/category\/case-study\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2026\/03\/Wordpress-4-2.png?fit=1200%2C628&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2026\/03\/Wordpress-4-2.png?fit=1200%2C628&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2026\/03\/Wordpress-4-2.png?fit=1200%2C628&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2026\/03\/Wordpress-4-2.png?fit=1200%2C628&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/nish.wales\/wp-content\/uploads\/2026\/03\/Wordpress-4-2.png?fit=1200%2C628&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":2846,"url":"https:\/\/nish.wales\/cy\/2025\/05\/21\/case-study-harnessing-gut-brain-signalling-to-boost-cognitive-health-in-parkinsons-dementia\/","url_meta":{"origin":4186,"position":2},"title":"Astudiaeth Achos: Signalau Coluddion-Ymennydd yn Hybu Iechyd Gwybyddol mewn Dementia Parkinson","author":"meganchick1","date":"21st Mai 2025","format":false,"excerpt":"Groundbreaking research at Swansea University is exploring the vital connection between gut hormones and brain function research that could pave the way for new treatments for cognitive decline in neurodegenerative diseases. 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